A Review on Pharmacological and Therapeutic Potential of Aloe barbadensis Miller
Deepak Sharma
School of Studies in Biochemistry, Jiwaji University, Gwalior - 474011, India.
Naimish Purohit
School of Studies in Biochemistry, Jiwaji University, Gwalior - 474011, India.
Shiwa Chaubey
CSIR- Phytochemistry Division, National Botanical Research Institute, Lucknow - 226001, India.
Mohan Tiwari
School of Studies in Biochemistry, Jiwaji University, Gwalior - 474011, India.
Mradu Bhadauriya
School of Studies in Biochemistry, Jiwaji University, Gwalior - 474011, India.
. Mohit
Department of Prosthodontics, Faculty of Dental Sciences, King George’s Medical University, Lucknow - 226003, India and Center for Advance Research, Faculty of Medicine, King George’s Medical University, Lucknow - 226003, India.
Nilam Bhasker
Department of Pathology, Employee State Insurance Corporation hospital, Lucknow - 226023, India.
Dharmendra Kumar *
Department of Orthopedic Surgery, Faculty of Medicine, King George’s Medical University, Lucknow - 226003, India.
*Author to whom correspondence should be addressed.
Abstract
Aloe vera, a popular succulent perennial medicinal plant with a wide range of phytochemicals that have shown various pharmacological activities including anti-oxidant, antimicrobial, antidiabetic, wound healing promotion and so on. Acemannan, aloe-emodin, aloin, aloesin, and emodin are widely investigated active constituents that show various pharmacological activities. Thus, the purpose of this review is to highlight previous pharmacological studied conducted in vivo, in vitro and human assays over the past decades. As current pharmacological research is focused on anticancer and neurological action, it would be interesting and important to study the main compounds present in Aloe vera for therapeutic purposes.
Keywords: Aloe vera, anti-oxidant, acemannan, aloe-emodin, emodin.