Phytochemical & Pharmacological Activities of Diospyros malabarica
Afnan Sayeid Himi
*
Department of Pharmacy, University of Asia Pacific, 74/A, Green Road, Farmgate, Dhaka - 1205, Bangladesh.
Manik Pramanik
Department of Pharmacy, Jagannath University, 9-10 Chittaranjan Avenue, Dhaka - 1100, Bangladesh.
Khadizatul Kubra
Department of Pharmacy, University of Asia Pacific, 74/A, Green Road, Farmgate, Dhaka - 1205, Bangladesh.
Maisha Muntaher
Department of Pharmacy, University of Asia Pacific, 74/A, Green Road, Farmgate, Dhaka - 1205, Bangladesh.
Khandaker Antara Anika
Department of Pharmacy, State University of Bangladesh, Kanchan Bridge, South Purbachal, Dhaka - 1461, Bangladesh.
Md. Ariful Islam
Department of Pharmacy, State University of Bangladesh, Kanchan Bridge, South Purbachal, Dhaka - 1461, Bangladesh.
Md. Sagar Mia
Department of Pharmaceutical Sciences, North South University, Bashundhara, Dhaka - 1229, Bangladesh.
*Author to whom correspondence should be addressed.
Abstract
Diospyros malabarica, is a prominent member of the Ebenaceae intimate natural to the Indian subcontinent. This paper comprehensively explores the diverse pharmacological activities attributed to various parts of Diospyros malabarica, shedding light on its possible as a foundation of bioactive composites for medicinal and therapeutic applications. The pharmacological properties of Diospyros malabarica are presented through an in-depth analysis of the scientific literature, highlighting its traditional uses, phytochemical constituents and therapeutic potential. This paper covers the wide array of bioactive compounds identified in Diospyros malabarica, which have been linked to its various pharmacological activities. Several studies have demonstrated its antimicrobial, antioxidant, anti-inflammatory, anti-diarrheal, anthelminthic and anti-diabetic properties. Additionally, Diospyros malabarica has shown promise as an anticancer agent, with its extracts exhibiting cytotoxic effects on various cancer cell lines. Furthermore, the paper underscores the importance of supplementary exploration to better understand the mechanisms of fundamental in the experimental pharmacological activities and to develop standardized formulations for clinical use. Diospyros malabarica emerges as a valuable botanical resource with rich pharmacological potential. Its traditional uses are supported by scientific evidence and its bioactive compounds hold promise for the development of novel therapeutic agents.
Keywords: Diospyros malabarica, Ebenaceae, gaub plant, malabar ebony, gabh, gabu, blackwood, TNF-alpha, IL-6