European Journal of Medicinal Plants

Ginger (Zingiber officinale Roscoe) was a revered rhizomatous herb known for its culinary and medicinal applications across various cultures. This review integrated traditional knowledge and modern scientific findings on ginger's therapeutic properties, particularly its ability to alleviate ailments such as nausea, digestive disorders, and respiratory issues. A detailed literature search was carried out using various databases, such as PubMed and Scopus. The focus was on peer-reviewed articles, ethnopharmacological surveys, and ancient texts, all published until 2024. Each source was carefully reviewed to ensure a thorough and informative exploration. Key bioactive compounds, including [6]-gingerol, [6]-shogaol, and zingerone, were identified for their potent anti-inflammatory, antioxidant, and anticancer effects. These compounds mitigated oxidative stress and inflammation, supporting ginger's role in managing conditions like arthritis and metabolic disorders. Recent studies clarified the biochemical mechanisms through which ginger produced these effects, including its ability to inhibit inflammatory pathways, enhance gastrointestinal function, alleviate nausea through receptor antagonism, and promote respiratory health. The review emphasized the rich historical importance of ginger in traditional healing practices, illustrating its revered status across cultures. Additionally, it substantiated its medicinal benefits through modern scientific research, bridging ancient wisdom with contemporary health insights for a comprehensive understanding of ginger's efficacy. The findings advocated for further clinical trials to explore ginger's therapeutic potential and its interactions with other treatments, reinforcing its value in integrative health practices. This synthesis underscored ginger's multifaceted benefits and its importance in promoting health and wellness.