Natural Medicines Enhancing Neurite Growth in Central Nervous System Disorders: A Review
M. Sudha
Department of Pharmacology, J.K.K. Nattraja College of Pharmacy, Kumarapalayam-638183, Tamilnadu, India
R. Shanmuga Sundaram *
Department of Pharmacology, J.K.K. Nattraja College of Pharmacy, Kumarapalayam-638183, Tamilnadu, India
V. Annapondian
Department of Pharmacology, J.K.K. Nattraja College of Pharmacy, Kumarapalayam-638183, Tamilnadu, India
B. R. Abhirama
Department of Pharmacology, J.K.K. Nattraja College of Pharmacy, Kumarapalayam-638183, Tamilnadu, India
Babitha K. Vazhayil
Department of Pharmacology, J.K.K. Nattraja College of Pharmacy, Kumarapalayam-638183, Tamilnadu, India
S. Gomathi
Department of Pharmacology, J.K.K. Nattraja College of Pharmacy, Kumarapalayam-638183, Tamilnadu, India
C. Geethapriya
Department of Pharmaceutical Chemistry, R.R. College of Pharmacy, Bangalore-66, Karnataka, India
Deepika Patel
Department of Pharmacology, Vinayaga Mission’s College of Pharmacy, Salem-638183, Tamilnadu, India
*Author to whom correspondence should be addressed.
Abstract
Aim: This review provides attention to different species of plants protecting neurons and enhancing neurite growth.
Methodology: Datas regarding the global burden of neurological disorders along with the use of different parts of the plant which provides traditional healing effect existing in some parts of the World were collected from studies carried out by several researchers.
Summary of Review: The phytochemical exploration of indigenous flora provided hundreds of CNS active plants covering the whole spectrum of activity such as psychoanaleptic, psycholeptic and psychodysleptic effects. Many studies have shown data for enhancing neurite outgrowth beyond neuroprotection.
Conclusion: Plants with various phytoconstituents such as flavonoids provide a safe therapeutic solution in reducing the burden of neurological disorders.
Keywords: Herbs, neurodegeneration, CNS, traditional medicines, flavanoids, neutraceuticals