Characterization of Phenolic Compounds of Ulva rigida (Chlorophycae) and Its Antioxidant Activity
Sana Mezghani *
Laboratory of Functional Neurophysiology and Pathology, Research Unit UR/11ES09, Department of Biological Sciences, Faculty of Science of Tunis, Tunis El Manar University, Tunis, Tunisia
Dezső Csupor
Department of Pharmacognosy, University of Szeged, Hungary
Ines Bourguiba
Laboratory of Functional Neurophysiology and Pathology, Research Unit UR/11ES09, Department of Biological Sciences, Faculty of Science of Tunis, Tunis El Manar University, Tunis, Tunisia
Judit Hohmann
Laboratory of Functional Neurophysiology and Pathology, Research Unit UR/11ES09, Department of Biological Sciences, Faculty of Science of Tunis, Tunis El Manar University, Tunis, Tunisia
Mohamed Amri
Laboratory of Functional Neurophysiology and Pathology, Research Unit UR/11ES09, Department of Biological Sciences, Faculty of Science of Tunis, Tunis El Manar University, Tunis, Tunisia
Mohamed Bouaziz
Laboratory of Electrochimistry and Environnement, École Nationale d’Ingénieurs de, Sfax BP ⟨1173⟩ 3038, University of Sfax, Sfax, Tunisia
*Author to whom correspondence should be addressed.
Abstract
Ulva rigida is a worldwide distributed green alga and is commenly used for human nutrition. Extracts of this seaweed were shown anti-hypercholestierinemic, antioxidant and anti-hyperglycemic activities. The antioxidant effect was often ascribed to the presence of a huge amount of polyphenols. The aim of this study was to characterise by high-performance liquid chromatography-electrospray ionisation mass spectrometry (HPLC-ESI-MS) the phenolic molecules present in extracts obtained from U. rigida. The antioxidant activities of different extracts were evaluated in vitro by DPPH assay and on HeLa cells culture.
Keywords: Ulva rigida, LC/MS, phenolic compounds, antioxidant, cytotoxicity