Anti-bacterial Effect of Chrysophyllum albidum Phyto Extract
I. A. Hassan *
Department of Biological Science, Lagos State Polytechnic, Ikorodu, Lagos State, Nigeria.
I. Abdulraheem
Department of Health Administration, Lagos State Polytechnic, Ikorodu, Lagos State, Nigeria.
H. O. Emun
Department of Hospitality Management Technology, Lagos State Polytechnic, Ikorodu, Lagos State, Nigeria.
O. M. Omole
Department of Biological Science, Lagos State Polytechnic, Ikorodu, Lagos State, Nigeria.
*Author to whom correspondence should be addressed.
Abstract
Aims: This study was carried out to investigate the antimicrobial activity of Chrysophyllum albidum leaves extract on selected Gastro-instestinal bacteria such as Salmonella typhimurium, Shigella dysentariae, Vibrio cholera, Escherichia coli and Clostridium perfringens.
Methodology: The leaves were extracted using ethanol, methanol and distilled water; the concentration of the extracts employed were 100 mg/ml, 200 mg/ml, 400 mg/ml and 500 mg/ml respectively; however the leaf extracts of Chrysophyllum albidum were screened for anti-microbial activity using the in vitro cup-plate method of agar diffusion technique with concentration of 10-5cells/ml of the selected bacteria. Simultaneously, 30 µg tetracycline and 30 µg metronidazole were used as positive control.
Results: The result showed that the most active among them is Tetracycline; followed by ethanolic extract, aqueous extract, methanolic extract and metronidazole extract respectively on the tested bacteria.
Conclusion: This research justifies the traditional use of the leaves of Chrysophyllum albidum for the therapeutic purposes; hence can be commercialized by pharmaceutical outfit; if not for anything but its availability and readily for human consumption.
Keywords: Anti-bacterial, Chrysophyllum albidum, extract, metronidazole and tetracycline.