Gestational Diabetes Review: Maternal-fetal Comorbidities and Treatment with Medicinal Plants
Saulo José de Lima Júnior
University of Gurupi, Av. Rio de Janeiro, Nº 1585 - St. Central, Gurupi, 77403-090, Tocantins, Brazil.
Tatyanne Milhomens Soares
University of Gurupi, Av. Rio de Janeiro, Nº 1585 - St. Central, Gurupi, 77403-090, Tocantins, Brazil.
Vanderson Ramos Mafra
University of Gurupi, Av. Rio de Janeiro, Nº 1585 - St. Central, Gurupi, 77403-090, Tocantins, Brazil.
Sara Falcão de Sousa
University of Gurupi, Av. Rio de Janeiro, Nº 1585 - St. Central, Gurupi, 77403-090, Tocantins, Brazil.
Jaqueline Cibene Moreira Borges
University of Gurupi, Av. Rio de Janeiro, Nº 1585 - St. Central, Gurupi, 77403-090, Tocantins, Brazil.
Natallia Moreira Lopes Leão
University of Gurupi, Av. Rio de Janeiro, Nº 1585 - St. Central, Gurupi, 77403-090, Tocantins, Brazil.
Andreisa Prieb
University of Gurupi, Av. Rio de Janeiro, Nº 1585 - St. Central, Gurupi, 77403-090, Tocantins, Brazil.
Yara Silveira
University of Gurupi, Av. Rio de Janeiro, Nº 1585 - St. Central, Gurupi, 77403-090, Tocantins, Brazil.
Rodrigues de Paula Marques
AVM Educational, Edifício Carmo - 5th floor, R. do Carmo, 07 - Centro, Rio de Janeiro, 20011-020, RJ, Brazil.
Nayanne Deusdará Escobar
University of Gurupi, Av. Rio de Janeiro, Nº 1585 - St. Central, Gurupi, 77403-090, Tocantins, Brazil.
Marco Túlio Borges Sousa
University of Gurupi, Av. Rio de Janeiro, Nº 1585 - St. Central, Gurupi, 77403-090, Tocantins, Brazil.
Thalita Melo França Costa
University of Gurupi, Av. Rio de Janeiro, Nº 1585 - St. Central, Gurupi, 77403-090, Tocantins, Brazil.
Taciano Peres Ferreira
Environmental Chemistry Collegiate, Federal University of Tocantins, Chácara 69-72 Rua Badejos, Lote 7 no number - Jardim Sevilha, Gurupi, 77404-970, Tocantins, Brazil.
Janne Marques Silveira
University of Gurupi, Av. Rio de Janeiro, Nº 1585 - St. Central, Gurupi, 77403-090, Tocantins, Brazil.
*Author to whom correspondence should be addressed.
Abstract
Gestational Diabetes is a condition characterized by hyperglycemia that provides a drop-in insulin performance in its appropriate receptors by hormones secreted by the placenta and fetus. The main fetal comorbidities are macrosomia, growth disorder, and congenital and maternal anomalies in gestational diabetes, preeclampsia, vascular injury, and post-gestational diabetes. This study addressed the possible treatments with medicinal plants in gestational diabetes. Medicinal plants that have the diabetic purpose were researched, however, many pregnant women use and do not know the effects that can happen for the fetus and also for itself, the plants used for this work is not satisfactory for pregnant women with diabetes, but for non-diabetics, some are beneficial for treating this pathology. It becomes necessary for people to know the effects of plants that are used to treat certain types of diseases because most often in great excess can be fatal. All of them presented satisfactory results in a study for diabetes mellitus in non-pregnant patients, but the study presented by Cow's Paw (Bauhinia forficata l.) in pregnant rats with diabetes showed harmful results in embryo implantation and there was no glycemic control, which leads us to investigate further under the use of all plants in the treatment of gestational diabetes.
Keywords: Gestational diabetes comorbidities, fetal risk factors, treatments with medicinal plants.