Pharmacological Properties and Chemical Constituents of Chiliadenus iphionoides (Syn. Varthemia iphionoides): A Review
Abeer R. Abdelhalim *
Department of Chemistry, College of Science, Taibah University, 30002, Al-Madinah Al-Munawarah, Saudi Arabia.
*Author to whom correspondence should be addressed.
Abstract
Chiliadenus iphionoides (Boiss. & Blanche) Brullo has been used in traditional medicine for different medical issues including stomach ailments, diabetes, male and female fertility problems, eye infection, kidney stones, and as an anti-inflammatory. Extracts of C. iphionoides have shown to exhibit useful pharmacological activities. Phytochemical studies have shown the existence of many biologically active compounds, such as essential oils, flavonoids, and phenolic compounds. This review aims to collect the published research about the traditional uses, chemical constituents, and pharmacological properties of C. iphionoides. This review showed that different extracts and active ingredients of C. iphionoides had various pharmacological properties such as anticancer, antidiabetic, antimicrobial, antioxidant, antispasmodic, and antiplatelet activities which might be due to the excitant of flavonoids and phenolic compounds. Chiliadenus iphionoides and its constituents exhibit many pharmacological properties that play a crucial role in human health, therefore, clinical trials should be conducted to study the valuable effects of the active ingredients of C. iphionoides in humans models and develop new drugs.
Keywords: Chiliadenus iphionoides, chemical constituents, pharmacological activities, traditional medicine, Varthemia iphionoides.