European Journal of Medicinal Plants <p style="text-align: justify;"><strong>European Journal of Medicinal Plants (ISSN: 2231-0894)</strong> is dedicated to publish&nbsp;high quality papers (<a href="/index.php/EJMP/general-guideline-for-authors">Click here for Types of paper</a>)&nbsp;in all areas of medicinal plants research including plant growth and development, agronomic management, plant nutrition, plant physiology, cell biology, molecular biology, biotechnology, medicinal properties, phytochemical constituents, fitoterapia, pharmacognosy, essential oils, ehnopharmacology and phytomedicine. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.</p> en-US (European Journal of Medicinal Plants) (European Journal of Medicinal Plants) Mon, 29 Jun 2020 00:00:00 +0000 OJS 60 Phytotherapy in Dentistry: A Literature Review Based on Clinical Data <p><strong>Aims: </strong>Looking for scientific support with an updated review about herbal medicines usage in dentistry for clinical application, reinforcing the potential of phytotherapics to treat oral disorders and the need for new studies on the topic.</p> <p><strong>Material and Methods:</strong> The literature search was performed combining “phytotherapy” and “dentistry” in the PubMed, MEDLINE, BBO, LILACS and SciELO databases, covering the period from January 2017 to March 2020. The data extracted were: Alteration/oral disease, gender, age, number of participants, herbal medicine used, drug function and results.</p> <p><strong>Results:</strong> were selected 24 papers that employed different plants, such as Tulsi, <em>Aloe vera</em>, citronella, turmeric, propolis and cloves. The results found are promising and show the anti-inflammatory, analgesic, antibacterial, antioxidant, antifungal, antiviral and tranquilizer action of herbal drugs, and their use for treating burning mouth syndrome, oral submucous fibrosis, xerostomia and halitosis.</p> <p><strong>Conclusion:</strong> despite the therapeutic activities of herbal medicines, additional studies with larger sample size and scientific rigor are necessary to prove their benefits for treating oral diseases.</p> Thaylla Núñez Amin Dick, Letícia Côgo Marques, Amanda de Almeida Lima Lopes, Monique Santana Candreva, Lílian Rocha Santos, Bruna Lavinas Sayed Picciani ##submission.copyrightStatement## Mon, 29 Jun 2020 00:00:00 +0000 Phenological Study of a Medicinally Important Plant Leonotis nepetifolia in Jharia Coal Field <p><em>Leonotis nepetifolia </em>(L.) R. Br. is a herbaceous plant belonging to the family Lamiaceae and grows across India by the roadsides or on the barren land field. This plant is medicinally very important. Various parts of the plant are used as depurative, febrifuge, antihelminthic, in relieving cough, in skin problems etc. But the ecology of this plant is also quite interesting. It can even survive the harsh conditions of Jharia coal field where the atmospheric conditions and edaphic factors are not favourable for the growth of various plants. But the plant, <em>Leonotis nepetifolia</em> grows luxuriantly in those stressful conditions as well. Keeping in view this ecological adaptability of this plant the present study was conducted with an objective to study the phenology of this particular plant in various conditions of Jharia coal field of Dhanbad district of Jharkhand so as to know how germination and flowering time of <em>Leonotis nepetifolia </em>changes with adversity so as to understand the ecological aspects quite better. For this, three stressful conditions were chosen where this plant was growing and their phenology was compared with that of the plant growing in controlled conditions. The phenology of this annual plant was found to be quite distinct in different places especially their germination time and death/dormancy.</p> Subir Kumar Khawas, P. K. Mishra ##submission.copyrightStatement## Mon, 29 Jun 2020 00:00:00 +0000 Cardioprotective Activities of Pterocarpus mildbraedii Leaves on Isoproterenol-induced Myocardial Infarction in Rats <p>The study evaluated the effects of <em>Pterocarpus mildbraedii</em> leaf extracts on myocardial infarction induced by isoproterenol (ISO) in Wistar albino rats with a view to ascertain the value of its use in the management of heart-related diseases. Fresh plant leaves were collected, identified, extracted, fractionated and the aqueous layer partitioned with ethyl acetate. GC-MS was carried out on the ethyl acetate fraction (EAF) and unknown compounds were identified by comparing measured mass spectral data with those in NIST 14 Mass Spectral Library. Twenty-five adult rats were divided into five groups of 5 rats each. Groups I &amp;II were the control groups. Rats in groups III-V were pretreated with 50 mg/kg and 100 mg/kg of EAF and 1.8 mg/kg of propranolol respectively for 21 days. Myocardial infarction was then induced in all the rats (except those in Group I) with the intraperitoneal injection of ISO (85 mg/kg) for 2 days. Afterwards, the rats were sacrificed and blood samples, heart homogenate and samples for histological studies were aseptically collected. Activities of cardiac biomarkers, lipid profile, enzymatic and non-enzymatic antioxidants were evaluated using standard methods. GC-MS analysis showed that the most abundant components of the plant are propionic acid, 2,3-dimethylphenyl ester, catechol, octyl-β-D-glucopyranoside, phenol and n-Hexadecanoic acid. Administration of ISO caused significant elevation of the activities of cardiac biomarkers (troponin-T concentrations, creatine kinase-MB and lactate dehydrogenase) while rats pretreated with EAF had significantly lower levels of the biomarkers. Moreover, alterations in lipid profile, enzymatic and non-enzymatic antioxidants brought about by the administration of ISO were ameliorated. Histological examinations revealed lesser degree of myocardial injury in pre-treated rats.</p> A. O. Fajobi, B. O. Emma- Okon, O. O. Oyedapo, C. A. Dare, A. O. Akinlalu, I. J. Komolafe, M. Ogunsusi ##submission.copyrightStatement## Thu, 02 Jul 2020 00:00:00 +0000 The Effect of Ginger on the Invasion and Migration of Glioma Cells <p><strong>Background:</strong> This work studies the effect of different concentrations of soaked ginger on the ability of the U87 glioma cells to invade collagen in a three dimension (3 D) invasion model and compare it with its effect on the ability of the same cell line to migrate in two-dimension (2 D) scratch assay.</p> <p><strong>Methods:</strong> The hanging drop spheroids in 3D invasion assay were used to investigate the in invasion of the U87 cells. The 2D scratch assay was used to investigate the migration of the same cell line.</p> <p><strong>Results:</strong> Gradual effect of the soaked ginger was noticed on the inhibition of the invasion of U87 in collagen and on the inhibition of the migration of the same cell line in scratch assay.</p> <p><strong>Conclusion:</strong> The results in this article are promising and encourage further studies to investigate the effect of ginger active ingredients on tumour progression.</p> Manar Zraikat, Munir Gharaibeh, Tasneem Alshelleh ##submission.copyrightStatement## Fri, 03 Jul 2020 00:00:00 +0000 Larvicidal and Adulticidal Activities of Neem Oil against Anastrepha fraterculus (Wied.) (Tephritidae) <p>In the laboratory, a neem oil-based formulation was evaluated for its insecticidal potential against the South American fruit fly <em>Anastrepha fraterculus</em> (Wied.), as efficient alternative for growers harvest fruits more harmless for the human consumption. The commercial product was evaluated against eggs <em>in vitro</em>, guavas infested with eggs and young larvae, and adults. The application of 0.8% neem oil significantly reduced the larval hatching of <em>A. fraterculus</em>. Neem oil at 0.4, 0.6 and 0.8% significantly reduced the number of pupae and adults per fruit infested with eggs. Guava infested with <em>A. fraterculus</em> eggs and treated with neem oil at 0.8% exhibited a reduction of 90.0% and 92.6% of pupae and adults per fruit, respectively. The same dosage to guava infested by larvae achieved a 44.6 and 51.4% reduction of pupae and larvae, respectively. At 360 minutes after treatment, 0.8% of neem oil provided 67.9% of corrected adult mortality. This double insecticidal effect of neem oil and lack of phytotoxicity in ripe guavas at the tested concentrations demonstrate its potential in biorational management.</p> Adalton Raga, Sara Braga e Silva, Léo Rodrigo Ferreira Louzeiro, Ester Marques de Sousa ##submission.copyrightStatement## Fri, 03 Jul 2020 00:00:00 +0000